NDVI calculation in boundary box

I am putting a boundary box overlay on sentinel-hub WMTS tile layer. Then, is it possible to calculate NDVI in this boundary box which is not calculated one in tile layer? My goal is to put several boundary boxes with independently adjusted NDVI colors in the same tile layer.

I am not sure I understand the question. Can you be more specific and provide some examples?

Does perhaps this FAQ answers it?

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If I understand correctly you want to calculate the NDVI within multiple rectangular bounding box geometries, but with different colour ramps for each bounding box? You can indeed clip the WMTS layer into multiple bounding box areas with the GEOMETRY parameter, but you won’t be able to apply separate colour ramps for each box - the colours within each box will be scaled based on the colour ramp definition you provide for the entire layer.